Mylan, a generic pharmaceutical manufacturer, will spend $100m in Ireland over the next five years to expand its operations in the cities of Dublin and Galway.
Through the investment, Mylan is expected to add more than 500 new positions to its Ireland-based workforce by 2016.
The company's investment will include funding for expanded research and development (R&D) capabilities with the support from the Irish government through the Irish Development Authority.
Mylan CEO Heather Bresch said: ''This investment in Mylan's Irish operations and the growth of our capabilities in the country demonstrate our continued commitment to and confidence in our respiratory franchise and injectables platform, both of which are among Mylan's many long-term growth drivers.''